Expert Comments On Oxidized Regenerated Cellulose

There are different opinions on the mechanism of action. First, due to its rough surface, it can promote platelet rupture, produce a large number of platelet coagulation factors, cause fibrinogen to turn into fibrin, form thrombi, block damaged blood vessels and stop bleeding. Its local hemostatic effect of oxidized regenerated cellulose is that the hydroxyl groups in cellulose form cross-links with Ca2+ in plasma to form gelatinous blood clots, which block damaged blood vessels and stop bleeding. Third, it is believed that oxidized regenerated cellulose does not participate in the normal physiological coagulation mechanism, but when it comes into contact with blood, cellulose turns into reddish brown or black gelatin blocks, which promotes the formation of blood clots.