What is oxidized regenerated cellulose?

Oxidized regenerated cellulose (ORC), as a cellulose derivative, has good biocompatibility, biodegradability and non-toxicity. Oxidized regenerated cellulose is cellulose that has been oxidized to become a cellulose acid gauze or cotton cloth-like absorbable hemostatic material. It has the appearance and texture of cotton gauze, is soft and thin, and is easy to wrap, stuff, etc. Its hemostatic mechanism is to aggregate the platelets in the blood on the wound surface on the mesh gauze, quickly forming a gel-like black substance to coagulate blood clots, thereby achieving the purpose of hemostasis. It does not rely on the normal coagulation mechanism in the human body, but quickly promotes blood coagulation through physical action, effectively controlling small blood vessel bleeding. The unique soft properties and texture allow it to be trimmed into any shape that fits the bleeding site, making it easier to fully contact the bleeding site, improving the hemostatic effect and helping to form a thrombus to achieve a rapid hemostatic effect. Its action characteristics are: (1) Rapid hemostasis. The quick gauze can be used as a hemostatic matrix to promote blood clot coagulation and accelerate the entire hemostasis process. Whether Suji gauze works does not depend on whether the coagulation mechanism in the body is normal. It has a significant effect on inhibiting bleeding in small blood vessels. The hemostasis effect can be achieved within 10 minutes through the endogenous mechanism. (2) Complete absorption: Suji gauze is basically completely absorbed after 7 days in the body, and has almost no specific reaction to the surrounding tissues. According to the author's clinical work, no toxic, allergic or rejection reactions have occurred during the treatment process. (3) Easy to use: Suji gauze is like a fabric and is very easy to adhere to irregular bleeding surfaces. It does not adhere to the surface of medical instruments such as instruments and gloves. It can be used by sewing, wrapping, filling and applying. It can be widely used in almost all surgical methods. Therefore, if ligation and other hemostasis methods are ineffective during surgery, Suji gauze can be used to stop bleeding in small arteries, capillaries and veins.